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Government or official record

Tamper-Resistant Packaging Requirements

U.S. Food and Drug Administration

Where this source supports the record

Each entry separates the article’s editorial relevance note from its exact, section-level claims. A bibliography link without a direct claim is labeled plainly.

  1. Historic crimes & investigations · 29 September–October 1982

    The Chicago Tylenol Murders

    Chicago metropolitan poisoning and investigation area · United States

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    Why editors use it here

    Official regulatory history and requirements created after product tampering.

    1. Quick read

      Beginning on 29 September 1982, seven people in the Chicago area died after taking Extra-Strength Tylenol capsules filled with cyanide.

      Reviewed 26 July 2026
    2. Trigger and conditions

      Twelve-year-old Mary Kellerman died after taking a capsule; postal worker Adam Janus died later that day, and two relatives died after taking capsules from his bottle while grieving.

      Reviewed 26 July 2026
    3. Uncertainty

      The deaths and cyanide contamination are established, but who altered the capsules, where, and why remain unknown.

      Reviewed 26 July 2026
    4. Why it matters

      A small number of altered objects changed the physical language of nearly every medicine package.

      Reviewed 26 July 2026